I visited Užupis in Vilnius in May, 2016
It was a beautiful, sunny day, people were sitting outside at every cafe I passed. The Old City of Vilnius looked beautiful in the sunlight, the old white and light colored walls shining. My airbnb hosts had given me directions to Užupiz: Head in the direction of the river, that way (as she pointed down the street). When you cross the river you are there.